protective effects of metformin on renal tubular cells
نویسندگان
چکیده
منابع مشابه
Protective Effects of Metformin on Renal Tubular Cells
Recently, we conducted a preclinical investigation to find the ameliorative properties of metformin on renal biochemical and histologic alterations of gentamicininduced kidney damage in male Wistar rats (1). In this investigation, attenuation of gentamicin-induced acute kidney injury was found. Likewise, Taheri et al. conducted a study on the effects of metformin on renal tubular cells after un...
متن کاملProtective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis.
ETHNOPHARMACOLOGICAL RELEVANCE Zhibai Dihuang Wan (ZDW) is an ancient traditional Chinese medicine composed of eight herbal ingredients and has been used to treat chronic kidney inflammation and diabetes for thousands of years. Nonetheless, the influence of ZDW on acute kidney injury is still unknown. We intended to identify the influence of ZDW on cell growth and gentamicin-induced apoptotic i...
متن کاملTangeretin protects renal tubular epithelial cells against experimental cisplatin toxicity
Objective(s): Cisplatin is an effective antineoplastic agent; its clinical utility, however, is limited by a few salient toxic side effects like nephrotoxicity. This study aimed to determine the potential protective effects of tangeretin, a citrus-derived flavonoid, against renal tubular cell injury in cisplatin-induced renal toxicity of rats.Materials and Methods: Tangeretin was injected intra...
متن کاملThe protective effects of ischemic postconditioning on renal tubular epithelial Epithelial-mesenchymal transition
Renal tubular Epithelial-mesenchymal transition (EMT) plays an important role in the process of renal fibrosis. The aim of this study is to observe the effects of ischemia post-conditioning on renal tubular Epithelialmesenchymal transition in vitro. A valid in vitro ischemia post-conditioning model was established by using NRK-52E cell line. The ischemic postconditioning (IPO) model was establi...
متن کاملCytotoxic effects of p-cresol in renal epithelial tubular cells.
BACKGROUND The uremic syndrome is characterized by a deterioration of kidney function due to the accumulation of uremic toxins. Currently, 100 different uremic toxins have been identified. Uremic toxins are particularly difficult to remove by conventional dialysis treatments and are the major causes of mortality in patients with chronic kidney disease (CKD). p-Cresol is a well-known uremic toxi...
متن کاملProtective and therapeutic effects of metformin on gynecologic cancers
Currently, in the aspect of drug repositioning, metformin which is the first line drug of choice for type 2 diabetes mellitus (T2DM) has been considered as a kind of therapeutic drug for gynecologic cancers based on its antitumor effects [1]. The main antitumor action of metformin occurs through activation of adenosine monophosphate activated protein kinase, which inhibits the phosphatidylinosi...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian red crescent medical journalجلد ۱۶، شماره ۹، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023